TANK 抗体 (N-Term)
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- 抗原 See all TANK 抗体
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 小鸡
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TANK antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 小鼠, 大鼠, 牛, 小鸡, 犬
- 纯化方法
- Purified
- 免疫原
- TANK antibody was raised in rabbit using the N terminal of TANK as the immunogen
- Top Product
- Discover our top product TANK Primary Antibody
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- 应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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TANK Blocking Peptide, catalog no. 33R-2027, is also available for use as a blocking control in assays to test for specificity of this TANK antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- 抗原
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- 别名
- TANK (TANK 产品)
- 别名
- I-TRAF antibody, ITRAF antibody, TRAF2 antibody, C86182 antibody, E430026L09Rik antibody, zgc:153048 antibody, i-traf antibody, tank antibody, traf2 antibody, TRAF family member associated NFKB activator antibody, TRAF family member-associated Nf-kappa B activator antibody, TRAF family member-associated NFKB activator antibody, TRAF family member associated NFKB activator L homeolog antibody, TANK antibody, Tank antibody, tank antibody, tank.L antibody
- 背景
- The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, TANK can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation.The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. Synonyms: Polyclonal TANK antibody, Anti-TANK antibody, TRAF family member-associated NFKB activator antibody, I-TRAF antibody, TRAF2 antibody.
- 途径
- p53 Pathway, TLR signaling, Activation of Innate immune Response
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