Insulin Receptor 抗体 (Middle Region)
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- 抗原 See all Insulin Receptor (INSR) 抗体
- Insulin Receptor (INSR)
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, 兔, 斑马鱼, 非洲爪蟾
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Insulin Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- 小鼠, 大鼠, 犬, 兔, 斑马鱼, Frog
- 纯化方法
- Purified
- 免疫原
- INSR antibody was raised in rabbit using the middle region of INSR as the immunogen
- Top Product
- Discover our top product INSR Primary Antibody
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- 应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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INSR Blocking Peptide, catalog no. 33R-8809, is also available for use as a blocking control in assays to test for specificity of this INSR antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- 抗原
- Insulin Receptor (INSR)
- 别名
- INSR (INSR 产品)
- 背景
- This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin. INSR binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). INSR can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. When present in a hybrid receptor with IGF1R, it binds IGF1. Synonyms: Polyclonal INSR antibody, Anti-INSR antibody, insulin receptor antibody, CD220 antibody, HHF5 antibody.
- 途径
- NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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