ZWINT 抗体 (AA 85-170) (AbBy Fluor® 555)
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- 抗原 See all ZWINT 抗体
- ZWINT (ZW10 Interactor (ZWINT))
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抗原表位
- AA 85-170
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZWINT antibody is conjugated to AbBy Fluor® 555
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ZWINT
- 亚型
- IgG
- Top Product
- Discover our top product ZWINT Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ZWINT (ZW10 Interactor (ZWINT))
- 别名
- ZWINT (ZWINT 产品)
- 别名
- ZWINT antibody, HZwint-1 antibody, KNTC2AP antibody, ZWINT1 antibody, 2010007E07Rik antibody, 2600001N01Rik antibody, D10Ertd749e antibody, Zwint-1 antibody, Sip30 antibody, ZW10 interacting kinetochore protein antibody, ZW10 interactor antibody, ZWINT antibody, Zwint antibody
- 背景
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Synonyms: HZwint1, KNTC 2 AP, KNTC2AP, MGC 117174, MGC117174, ZW10 interacting protein 1, ZW10 interactor, ZWINT 1, ZWINT1, ZWINT-1, ZWINT_HUMAN.
Background: ZWINT is a component of the MIS12 complex, which is required for kinetochore function and spindle checkpoint activity. ZWINT interacts with ZW10 and targets it to the kinetochore at prometaphase. ZWINT is detectable on the kinetochore till late anaphase. Inhibition of ZWINT expression results in chromosome missegregation, spindle checkpoint failure and, ultimately, cell death upon cytokinesis.
- 基因ID
- 11130
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