TNIP2 抗体 (AA 85-180) (AbBy Fluor® 647)
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- 抗原 See all TNIP2 抗体
- TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))
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抗原表位
- AA 85-180
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNIP2 antibody is conjugated to AbBy Fluor® 647
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TNIP2/ABIN2
- 亚型
- IgG
- Top Product
- Discover our top product TNIP2 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))
- 别名
- TNIP2 (TNIP2 产品)
- 别名
- MGC83548 antibody, TNIP2 antibody, ABIN2 antibody, FLIP1 antibody, KLIP antibody, 1810020H16Rik antibody, ABIN-2 antibody, AI428870 antibody, TNFAIP3 interacting protein 2 antibody, TNFAIP3 interacting protein 2 L homeolog antibody, TNIP2 antibody, tnip2.L antibody, tnip2 antibody, Tnip2 antibody
- 背景
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Synonyms: KLIP, ABIN2, FLIP1, TNFAIP3-interacting protein 2, A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, Fetal liver LKB1-interacting protein, TNIP2
Background: Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response, this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells, promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes.
- 基因ID
- 79155
- UniProt
- Q8NFZ5
- 途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin
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