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TNIP2 抗体 (AA 85-180) (AbBy Fluor® 647)

TNIP2 适用: 人, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 647
产品编号 ABIN918179
发货至: 中国
  • 抗原 See all TNIP2 抗体
    TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))
    抗原表位
    • 14
    • 8
    • 7
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 85-180
    适用
    • 46
    • 23
    • 13
    • 1
    人, 大鼠
    宿主
    • 48
    克隆类型
    • 48
    多克隆
    标记
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNIP2 antibody is conjugated to AbBy Fluor® 647
    应用范围
    • 37
    • 20
    • 12
    • 12
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 大鼠
    预测反应
    Mouse,Dog,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human TNIP2/ABIN2
    亚型
    IgG
    Top Product
    Discover our top product TNIP2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))
    别名
    TNIP2 (TNIP2 产品)
    别名
    MGC83548 antibody, TNIP2 antibody, ABIN2 antibody, FLIP1 antibody, KLIP antibody, 1810020H16Rik antibody, ABIN-2 antibody, AI428870 antibody, TNFAIP3 interacting protein 2 antibody, TNFAIP3 interacting protein 2 L homeolog antibody, TNIP2 antibody, tnip2.L antibody, tnip2 antibody, Tnip2 antibody
    背景

    Synonyms: KLIP, ABIN2, FLIP1, TNFAIP3-interacting protein 2, A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, Fetal liver LKB1-interacting protein, TNIP2

    Background: Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response, this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells, promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes.

    基因ID
    79155
    UniProt
    Q8NFZ5
    途径
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin
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