SLC29A4 抗体 (AA 401-500) (AbBy Fluor® 647)
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- 抗原 See all SLC29A4 抗体
- SLC29A4 (Solute Carrier Family 29 (Nucleoside Transporters), Member 4 (SLC29A4))
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抗原表位
- AA 401-500
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC29A4 antibody is conjugated to AbBy Fluor® 647
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Cow,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SLC29A4
- 亚型
- IgG
- Top Product
- Discover our top product SLC29A4 Primary Antibody
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- 应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- SLC29A4 (Solute Carrier Family 29 (Nucleoside Transporters), Member 4 (SLC29A4))
- 别名
- SLC29A4 (SLC29A4 产品)
- 别名
- zgc:158679 antibody, ENT4 antibody, PMAT antibody, mPMAT antibody, solute carrier family 29 (equilibrative nucleoside transporter), member 4 antibody, solute carrier family 29 member 4 antibody, solute carrier family 29 (nucleoside transporters), member 4 antibody, slc29a4 antibody, SLC29A4 antibody, Slc29a4 antibody
- 背景
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Synonyms: ENT4, PMAT, Equilibrative nucleoside transporter 4, hENT4, Plasma membrane monoamine transporter, Solute carrier family 29 member 4, SLC29A4, PSEC0113
Background: Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH , with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
- 基因ID
- 222962
- UniProt
- Q7RTT9
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