RPS3 抗体 (AA 101-200) (Biotin)
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- 抗原 See all RPS3 抗体
- RPS3 (Ribosomal Protein S3 (RPS3))
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抗原表位
- AA 101-200
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适用
- 人, 小鼠, 非洲爪蟾
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RPS3 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 非洲爪蟾
- 预测反应
- Rat,Zebrafish
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RPS3
- 亚型
- IgG
- Top Product
- Discover our top product RPS3 Primary Antibody
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anti-Ribosomal Protein S3 (RPS3) (AA 1-243) antibody
RPS3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S3 (RPS3) antibodyRPS3 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S3 (RPS3) antibodyRPS3 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S3 (RPS3) (Internal Region) antibodyRPS3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S3 (RPS3) (AA 144-243) antibodyRPS3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A8 unconjugated
anti-Ribosomal Protein S3 (RPS3) antibodyRPS3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S3 (RPS3) antibodyRPS3 适用: 人 WB, IHC, ELISA, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S3 (RPS3) (AA 101-200) antibodyRPS3 适用: 人, 小鼠, 非洲爪蟾 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S3 (RPS3) (C-Term) antibodyRPS3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S3 (RPS3) (C-Term) antibodyRPS3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- RPS3 (Ribosomal Protein S3 (RPS3))
- 别名
- RPS3 (RPS3 产品)
- 背景
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Synonyms: S3, 40S ribosomal protein S3, RPS3, OK/SW-cl.26
Background: Involved in translation as a component of the 40S small ribosomal subunit (PubMed:8706699). Has endonuclease activity and plays a role in repair of damaged DNA (PubMed:7775413). Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (PubMed:15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (PubMed:14706345). Has also been shown to bind with similar affinity to intact and damaged DNA (PubMed:18610840). Stimulates the N-glycosylase activity of the base excision protein OGG1 (PubMed:15518571). Enhances the uracil excision activity of UNG1 (PubMed:18973764). Also stimulates the cleavage of the phosphodiester backbone by APEX1 (PubMed:18973764). When located in the mitochondrion, reduces cellular ROS levels and mitochondrial DNA damage (PubMed:23911537). Has also been shown to negatively regulate DNA repair in cells exposed to hydrogen peroxide (PubMed:17049931). Plays a role in regulating transcription as part of the NF-kappa-B p65-p50 complex where it binds to the RELA/p65 subunit, enhances binding of the complex to DNA and promotes transcription of target genes (PubMed:18045535). Represses its own translation by binding to its cognate mRNA (PubMed:20217897). Binds to and protects TP53/p53 from MDM2-mediated ubiquitination (PubMed:19656744). Involved in spindle formation and chromosome movement during mitosis by regulating microtubule polymerization (PubMed:23131551). Involved in induction of apoptosis through its role in activation of CASP8 (PubMed:14988002). Induces neuronal apoptosis by interacting with the E2F1 transcription factor and acting synergistically with it to up-regulate pro-apoptotic proteins BCL2L11/BIM and HRK/Dp5 (PubMed:20605787). Interacts with TRADD following exposure to UV radiation and induces apoptosis by caspase-dependent JNK activation (PubMed:22510408).
- 基因ID
- 6188
- UniProt
- P23396
- 途径
- Positive Regulation of Endopeptidase Activity
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