PLSCR3 抗体 (AA 201-295) (Biotin)
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- 抗原 See all PLSCR3 抗体
- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
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抗原表位
- AA 201-295
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLSCR3 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PLSCR3
- 亚型
- IgG
- Top Product
- Discover our top product PLSCR3 Primary Antibody
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
- 别名
- PLSCR3 (PLSCR3 产品)
- 别名
- 2210403O21Rik antibody, 2610037N06Rik antibody, ESTM3 antibody, X83310 antibody, Pls3 antibody, zgc:77051 antibody, phospholipid scramblase 3 antibody, phospholipid scramblase 3b antibody, PLSCR3 antibody, Plscr3 antibody, plscr3b antibody
- 背景
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Synonyms: Ca2+-dependent phospholipid scramblase 3, Phospholipid scramblase 3, PL scramblase 3, PLS3, PLS3_HUMAN.
Background: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.
- 基因ID
- 57048
- 途径
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
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