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PLCz1 抗体 (AA 351-450) (AbBy Fluor® 350)

PLCz1 适用: 大鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN911373
发货至: 中国
  • 抗原 See all PLCz1 抗体
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    抗原表位
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    适用
    • 20
    • 14
    • 4
    大鼠
    宿主
    • 33
    • 2
    克隆类型
    • 33
    • 2
    多克隆
    标记
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLCz1 antibody is conjugated to AbBy Fluor® 350
    应用范围
    • 12
    • 12
    • 12
    • 10
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PLCZ1
    亚型
    IgG
    Top Product
    Discover our top product PLCz1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    别名
    PLCZ1 (PLCz1 产品)
    别名
    PLC-zeta-1 antibody, PLCZ1 antibody, 1700041H07Rik antibody, PLCzeta antibody, NYD-SP27 antibody, PLCZ antibody, phospholipase C zeta 1 antibody, phospholipase C, zeta 1 antibody, PLCZ1 antibody, Plcz1 antibody
    背景

    Synonyms: PLCzeta, NYD-SP27, PLC-zeta-1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, Phosphoinositide phospholipase C-zeta-1, Phospholipase C-zeta-1, Testis-development protein NYD-SP27, PLCZ1, PLCZ1_HUMAN

    Background: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.

    基因ID
    89869
    UniProt
    Q86YW0
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