PLAG1 抗体 (AbBy Fluor® 350)
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- 抗原 See all PLAG1 抗体
- PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLAG1 antibody is conjugated to AbBy Fluor® 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PLAG1
- 亚型
- IgG
- Top Product
- Discover our top product PLAG1 Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))
- 别名
- Plag1 (PLAG1 产品)
- 别名
- PLAG1 antibody, MGC152687 antibody, PSA antibody, SGPA antibody, ZNF912 antibody, PLAG1 zinc finger antibody, pleiomorphic adenoma gene 1 antibody, PLAG1 antibody, plag1 antibody, Plag1 antibody
- 背景
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Synonyms: PSA, SGPA, ZNF912, Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein, PLAG1
Background: Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.
- 基因ID
- 5324
- UniProt
- Q6DJT9
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