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PLAG1 抗体 (AbBy Fluor® 350)

PLAG1 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN911308
发货至: 中国
  • 抗原 See all PLAG1 抗体
    PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))
    适用
    • 45
    • 33
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    人, 小鼠, 大鼠
    宿主
    • 57
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    克隆类型
    • 58
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    多克隆
    标记
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    This PLAG1 antibody is conjugated to AbBy Fluor® 350
    应用范围
    • 54
    • 19
    • 12
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PLAG1
    亚型
    IgG
    Top Product
    Discover our top product PLAG1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))
    别名
    Plag1 (PLAG1 产品)
    别名
    PLAG1 antibody, MGC152687 antibody, PSA antibody, SGPA antibody, ZNF912 antibody, PLAG1 zinc finger antibody, pleiomorphic adenoma gene 1 antibody, PLAG1 antibody, plag1 antibody, Plag1 antibody
    背景

    Synonyms: PSA, SGPA, ZNF912, Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein, PLAG1

    Background: Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.

    基因ID
    5324
    UniProt
    Q6DJT9
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