TSPO 抗体 (AA 31-130) (AbBy Fluor® 488)
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- 抗原 See all TSPO 抗体
- TSPO (Peripheral-Type Benzodiazepine Receptor (TSPO))
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抗原表位
- AA 31-130
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TSPO antibody is conjugated to AbBy Fluor® 488
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Peripheral type Benzodiazepine Receptor
- 亚型
- IgG
- Top Product
- Discover our top product TSPO Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- TSPO (Peripheral-Type Benzodiazepine Receptor (TSPO))
- 别名
- PBR (TSPO 产品)
- 别名
- LOC732875 antibody, LOC100136652 antibody, LOC100280949 antibody, BZRP antibody, TSPO antibody, Bzrp antibody, IBP antibody, PBR antibody, Tspo1 antibody, MBR antibody, PTBZR02 antibody, Ptbzr antibody, RATPTBZR02 antibody, BPBS antibody, DBI antibody, PBS antibody, PKBS antibody, PTBR antibody, mDRC antibody, pk18 antibody, peripheral-type benzodiazepine receptor antibody, Peripheral-type benzodiazepine receptor antibody, putative peripheral-type benzodiazepine receptor antibody, translocator protein antibody, translocator protein homolog antibody, hypothetical protein antibody, LOC732875 antibody, MAV_3896 antibody, xccb100_2086 antibody, Smp_102510 antibody, Sros_1911 antibody, tspo antibody, LOC100280949 antibody, PGTG_16395 antibody, TSPO antibody, Tspo antibody
- 背景
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Synonyms: BPBS, BZRP, DBI, IBP, Isoquinoline carboxamide-binding protein, MBR, mDRC, Mitochondrial benzodiazepine receptor, PBR, PBS, Peripheral benzodiazepine receptor, Peripheral benzodiazepine receptor-related protein, Peripheral type benzodiazepine receptor, pk18, PKBS, PTBR, Ptbzr, PTBZR02, RATPTBZR02, translocator protein 18 kDa, Translocator protein, TSPO, Tspo1, Benzodiazapine receptor peripheral, Benzodiazepine peripheral binding site.
Background: PBR (Peripheral type Benzodiazepine Receptor) is a ubiquitous protein (18 kDa) found in most steroidogenic tissues. It is located primarily in the outer mitochondrial membrane of steroid producing tissues and is found in association with a 34 kDa voltage dependent anion channel protein (VDAC). PBR interacts with some benzodiazepines and has different affinities than its endogenous counterpart. PBR appears to be a key factor in the transport of cholesterol from the outer to the inner mitochondrial membrane to permit the initiation of steroid hormone synthesis. It is thought to be part of the mitochondrial permeability transition pore (PT) and to be involved in apoptosis. It is speculated that patients with congenital lipoid adrenal hyperplasia, who cannot make any steroids, might have a genetic lesion in BZRP. A short form, PBRS is also expressed in the same tissues, but at a level about ten times that of PBR.
- 基因ID
- 1622
- 途径
- Cellular Response to Molecule of Bacterial Origin
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