NLRP4 抗体 (AA 351-450) (Cy7)
-
- 抗原 See all NLRP4 抗体
- NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))
-
抗原表位
- AA 351-450
-
适用
- 人, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This NLRP4 antibody is conjugated to Cy7
-
应用范围
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 特异性
- This antibody will detect multiple forms of NALP4, including the A, C and E Mouse variants.
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NALP4
- 亚型
- IgG
- Top Product
- Discover our top product NLRP4 Primary Antibody
-
anti-NLR Family, Pyrin Domain Containing 4 (NLRP4) (AA 351-450) antibody
NLRP4 适用: 人, 大鼠 ELISA, IF (p), IF (cc), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 4 (NLRP4) (AA 121-149) antibodyNLRP4 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))
- 别名
- NALP4 (NLRP4 产品)
- 别名
- CLR19.5 antibody, CT58 antibody, NALP4 antibody, PAN2 antibody, PYPAF4 antibody, RNH2 antibody, Nalp4 antibody, Nlrp4e antibody, RGD1563529 antibody, NLR family pyrin domain containing 4 antibody, NLR family, pyrin domain containing 4 antibody, NLRP4 antibody, Nlrp4 antibody
- 背景
-
Synonyms: NACHT, LRR and PYD domains-containing protein 4, Cancer/testis antigen 58, CT58, PAAD and NACHT-containing protein 2, PAN2, PYRIN and NACHT-containing protein 2, PYRIN-containing APAF1-like protein 4, PYPAF4, Ribonuclease inhibitor 2, NLRP4, NALP4, RNH2
Background: May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, suggesting that it operates at a point of convergence in these two cytokine signaling pathways.
- 基因ID
- 147945
- UniProt
- Q96MN2
- 途径
- Inflammasome
-
