NLRP12 抗体 (AA 176-270) (Biotin)
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- 抗原 See all NLRP12 抗体
- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
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抗原表位
- AA 176-270
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NLRP12 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NALP12
- 亚型
- IgG
- Top Product
- Discover our top product NLRP12 Primary Antibody
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anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 1-110) antibody
NLRP12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B9 unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 183-212), (N-Term) antibodyNLRP12 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33963 unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 183-212) antibodyNLRP12 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) antibodyNLRP12 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (Internal Region) antibodyVerified NLRP12 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 862-1062) antibodyNLRP12 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 862-1062) antibodyNLRP12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) antibodyNLRP12 适用: 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 228CT4-1-3 unconjugated
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
- 别名
- NALP12 (NLRP12 产品)
- 背景
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Synonyms: CLR19.3, FCAS2, Monarch 1, Monarch-1, NACHT, leucine rich repeat and PYD containing 12, NACHT, LRR and PYD containing protein 12, NACHT, LRR and PYD domains-containing protein 12, NAL12_HUMAN, NLR family, pyrin domain containing 12, NLRP12, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12, PAN6, PYPAF7, PYRIN containing APAF1 like protein 7, PYRIN-containing APAF1-like protein 7, Regulated by nitric oxide, RNO, RNO2.
Background: May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.
- 基因ID
- 91662
- 途径
- Positive Regulation of Endopeptidase Activity, Inflammasome
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