MMP26 抗体 (AA 185-261) (AbBy Fluor® 488)
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- 抗原 See all MMP26 抗体
- MMP26 (Matrix Metallopeptidase 26 (MMP26))
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抗原表位
- AA 185-261
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MMP26 antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MMP26 intermedial
- 亚型
- IgG
- Top Product
- Discover our top product MMP26 Primary Antibody
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anti-Matrix Metallopeptidase 26 (MMP26) (AA 152-261) antibody
MMP26 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C6 unconjugated
anti-Matrix Metallopeptidase 26 (MMP26) (AA 152-261) antibodyMMP26 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B9 unconjugated
anti-Matrix Metallopeptidase 26 (MMP26) (AA 152-261) antibodyMMP26 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B9 unconjugated
anti-Matrix Metallopeptidase 26 (MMP26) (AA 90-261) antibodyMMP26 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 26 (MMP26) (C-Term) antibodyMMP26 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 26 (MMP26) (AA 96-125) antibodyMMP26 适用: 人 WB 宿主: 兔 Polyclonal RB41665 unconjugated
anti-Matrix Metallopeptidase 26 (MMP26) (C-Term) antibodyMMP26 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MMP26 (Matrix Metallopeptidase 26 (MMP26))
- 别名
- Mmp-26 (MMP26 产品)
- 别名
- matrix metallopeptidase 26 antibody, MMP26 antibody
- 背景
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Synonyms: MMP26_HUMAN, Endometase, Matrilysin 2, MMP26, Matrix Metalloproteinase 26, MMP 26.
Background: Matrix metalloproteinase 26 preprotein, gelatinase A, 70kD type IV collagenase, gelatinase neutrophil. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes as well as in disease processes. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP26 degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP26, also known as Matrilysin 2, was first cloned from human fetal cells, and identified as an MMP most closely related to MMP7 (Matrilysin 1). The homology between MMP7 and MMP26 is low (only 38 % identical), thus the functions are unlikely to be similar. Homology is much higher (48 % identical) for the comparable region of MMP12, but MMP26 appears to have broader substrate specificity than does MMP12. MMP26, like MMP7, lacks the hemopexin domain common to the other MMPs, but contains a Propeptide domain, cysteine switch activation site, followed by a catalytic domain, and a short vestige of the hinge region. MMP26 is apparently not glycosylated, and is a secreted MMP. Tissue analysis shows MMP26 most strongly in placenta and uterus, but also in kidney cells, lung cells, lymphocytes and lung or endometrial carcinoma cells. MMP26 is proteolytically active, cleaving casein in zymograms, and gelatin, a1PI, fibrinogen, fibronectin, vitronectin, type IV collagen, and apparently activating MMP9.
- 基因ID
- 56547
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