MASP1 抗体 (AA 20-120) (AbBy Fluor® 488)
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- 抗原 See all MASP1 抗体
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
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抗原表位
- AA 20-120
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MASP1 antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MASP
- 亚型
- IgG
- Top Product
- Discover our top product MASP1 Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- 别名
- Masp (MASP1 产品)
- 别名
- AW048060 antibody, CCPII antibody, Crarf antibody, Masp1/3 antibody, 3MC1 antibody, CRARF antibody, CRARF1 antibody, MAP1 antibody, MASP antibody, MASP3 antibody, MAp44 antibody, PRSS5 antibody, RaRF antibody, mannan-binding lectin serine peptidase 1 antibody, mannan binding lectin serine peptidase 1 antibody, Masp1 antibody, MASP1 antibody
- 背景
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Synonyms: 3MC1, MAP1, MASP, RaRF, CRARF, MASP3, MAp44, PRSS5, CRARF1, Mannan-binding lectin serine protease 1, Complement factor MASP-3, Complement-activating component of Ra-reactive factor, Mannose-binding lectin-associated serine protease 1, MASP-1, Mannose-binding protein-associated serine protease, Ra-reactive factor serine protease p100, Serine protease 5, MASP1
Background: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
- 基因ID
- 5648
- UniProt
- P48740
- 途径
- Complement System
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