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DDX11 抗体 (AA 231-330) (Biotin)

DDX11 适用: 人 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN904303
发货至: 中国
  • 抗原 See all DDX11 抗体
    DDX11 (DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11))
    抗原表位
    • 14
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    AA 231-330
    适用
    • 71
    • 24
    • 15
    宿主
    • 67
    • 4
    克隆类型
    • 70
    • 1
    多克隆
    标记
    • 18
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DDX11 antibody is conjugated to Biotin
    应用范围
    • 64
    • 34
    • 27
    • 26
    • 26
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DDX11
    亚型
    IgG
    Top Product
    Discover our top product DDX11 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    DDX11 (DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11))
    别名
    DDX11 (DDX11 产品)
    别名
    CHL1 antibody, CHLR1 antibody, KRG2 antibody, WABS antibody, 4732462I11Rik antibody, essa15a antibody, putative ATP-dependent RNA helicase DDX11-like protein 8 antibody, DEAD/H-box helicase 11 antibody, DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 antibody, LOC100448472 antibody, DDX11 antibody, Ddx11 antibody
    背景

    Synonyms: CHL1, CHL1 related helicase gene 1, CHL1-like helicase homolog, CHL1-related protein 1, CHLR1, Ddx11, DDX11_HUMAN, DEAD/H Asp Glu Ala Asp/His box polypeptide 11, DEAD/H box protein 11, hCHLR1, Keratinocyte growth factor regulated gene 2 protein, Keratinocyte growth factor-regulated gene 2 protein, KRG 2, KRG-2, KRG2, Probable ATP dependent RNA helicase DDX11, Probable ATP-dependent RNA helicase DDX11.

    Background: DNA helicase involved in cellular proliferation. Possesses DNA-dependent ATPase and helicase activities. This helicase translocates on single-stranded DNA in the 5' to 3' direction in the presence of ATP and, to a lesser extent, dATP. Its unwinding activity requires a 5'-single-stranded region for helicase loading, since flush-ended duplex structures do not support unwinding. The helicase activity is capable of displacing duplex regions up to 100 bp, which can be extended to 500 bp by RPA or the cohesion establishment factor, the Ctf18-RFC (replication factor C) complex activities. Stimulates the flap endonuclease activity of FEN1. Required for normal sister chromatid cohesion. Required for recruitement of bovine papillomavirus type 1 regulatory protein E2 to mitotic chrmosomes and for viral genome maintenance. Required for maintaining the chromosome segregation and is essential for embryonic development and the prevention of aneuploidy. May function during either S, G2, or M phase of the cell cycle. Binds to both single- and double-stranded DNA.Tissue specificity: Highly expressed in spleen, B-cells, thymus, testis, ovary, small intestine, and pancreas. Very low expression seen in the brain. Expressed in dividing cells and/or cells undergoing high levels of recombination. No expression is seen in cells signaled to terminally differentiate. Expressed in keratinocyte growth factor-stimulated cells but not in serum, EGF and IL1-beta-treated keratinocytes.

    基因ID
    1663
    途径
    ER-Nucleus Signaling
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