KCNMB1 抗体 (AA 10-80) (AbBy Fluor® 647)
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- 抗原 See all KCNMB1 抗体
- KCNMB1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1))
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抗原表位
- AA 10-80
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNMB1 antibody is conjugated to AbBy Fluor® 647
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human KCNMB1
- 亚型
- IgG
- Top Product
- Discover our top product KCNMB1 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- KCNMB1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1))
- 别名
- KCNMB1 (KCNMB1 产品)
- 别名
- KCNMB1 antibody, BKbeta1 antibody, K(VCA)beta antibody, SLO-BETA antibody, hbeta1 antibody, hslo-beta antibody, k(VCA)beta-1 antibody, slo-beta-1 antibody, BKBETA antibody, potassium calcium-activated channel subfamily M regulatory beta subunit 1 antibody, potassium large conductance calcium-activated channel, subfamily M, beta member 1 antibody, KCNMB1 antibody, Kcnmb1 antibody
- 背景
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Synonyms: Calcium-activated potassium channel subunit beta-1, KCNMB1, BK channel subunit beta-1, Charybdotoxin receptor subunit beta-1, K(VCA)beta-1, Maxi K channel subunit beta-1, Slo-beta-1, Slo-beta
Background: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca2+/voltage sensitivity of the KCNMA1 channel. It also modifies KCNMA1 channel kinetics and alters its pharmacological properties. It slows down the activation and the deactivation kinetics of the channel. Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1. Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2). Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate.
- 基因ID
- 3779
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