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IL17C 抗体 (AA 101-197) (AbBy Fluor® 555)

IL17C 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 555
产品编号 ABIN902223
发货至: 中国
  • 抗原 See all IL17C 抗体
    IL17C (Interleukin 17C (IL17C))
    抗原表位
    • 14
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-197
    适用
    • 37
    • 20
    • 16
    • 3
    人, 小鼠, 大鼠
    宿主
    • 32
    • 6
    • 2
    • 1
    克隆类型
    • 35
    • 6
    多克隆
    标记
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL17C antibody is conjugated to AbBy Fluor® 555
    应用范围
    • 30
    • 13
    • 12
    • 12
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human IL-17C
    亚型
    IgG
    Top Product
    Discover our top product IL17C Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL17C (Interleukin 17C (IL17C))
    别名
    IL-17C (IL17C 产品)
    别名
    IL17C antibody, il17-3 antibody, CX2 antibody, IL-17C antibody, IL-21 antibody, interleukin 17C antibody, interleukin 17c antibody, IL17C antibody, il17c antibody, Il17c antibody
    背景

    Synonyms: CX2, IL-17C, Interleukin-17C, Cytokine CX2, IL17C, UNQ561/PRO1122

    Background: Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.

    基因ID
    27189
    UniProt
    Q9P0M4
    途径
    Cellular Response to Molecule of Bacterial Origin
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