IER3 抗体 (AA 85-156) (Biotin)
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- 抗原 See all IER3 抗体
- IER3 (Immediate Early Response 3 (IER3))
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抗原表位
- AA 85-156
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IER3 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein
- 亚型
- IgG
- Top Product
- Discover our top product IER3 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- IER3 (Immediate Early Response 3 (IER3))
- 别名
- IEX1 (IER3 产品)
- 别名
- DIF-2 antibody, DIF2 antibody, GLY96 antibody, IEX-1 antibody, IEX-1L antibody, IEX1 antibody, PRG1 antibody, AI663993 antibody, cI-3 antibody, gly96 antibody, IER3 antibody, Dif2 antibody, Iex1 antibody, Ler3 antibody, Prg1 antibody, immediate early response 3 antibody, IER3 antibody, Ier3 antibody
- 背景
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Synonyms: DIF2, IEX1, PRG1, DIF-2, GLY96, IEX-1, IEX-1L, Radiation-inducible immediate-early gene IEX-1, Differentiation-dependent gene 2 protein, Protein DIF-2, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, Protein PRG1, IER3
Background: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
- 基因ID
- 8870
- UniProt
- P46695
- 途径
- Regulation of Carbohydrate Metabolic Process
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