DOCK1 抗体 (AA 465-550) (Biotin)
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- 抗原 See all DOCK1 抗体
- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
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抗原表位
- AA 465-550
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DOCK1 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DOCK1
- 亚型
- IgG
- Top Product
- Discover our top product DOCK1 Primary Antibody
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
- 别名
- DOCK1 (DOCK1 产品)
- 别名
- DOCK180 antibody, ced5 antibody, 9130006G06Rik antibody, AI854900 antibody, D630004B07Rik antibody, RGD1566072 antibody, dedicator of cytokinesis 1 antibody, dedicator of cytokinesis protein 1 antibody, dedicator of cyto-kinesis 1 antibody, DOCK1 antibody, Dock1 antibody, dock1 antibody, CpipJ_CPIJ002759 antibody
- 背景
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Synonyms: 180 kDa protein downstream of CRK, Ced5, Dedicator of Cytokinesis 1, Dedicator of cytokinesis protein 1, DOCK 1, DOCK-1, DOCK 180, DOCK1, DOCK1_HUMAN, DOCK180.
Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
- 基因ID
- 1793
- 途径
- Signaling of Hepatocyte Growth Factor Receptor
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