CPB2 抗体 (AA 131-230) (Biotin)
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- 抗原 See all CPB2 抗体
- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
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抗原表位
- AA 131-230
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CPB2 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CPB2
- 亚型
- IgG
- Top Product
- Discover our top product CPB2 Primary Antibody
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anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 113-422) antibody
CPB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 138-386) antibodyCPB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 187-327) antibodyCPB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 225-372) antibodyCPB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 164-417) antibodyCPB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 1-423) antibodyCPB2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 1-423) antibodyCPB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 166-388) antibodyCPB2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) antibodyCPB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 324-373) antibodyCPB2 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
- 别名
- CPB2 (CPB2 产品)
- 别名
- CPU antibody, PCPB antibody, TAFI antibody, 1110032P04Rik antibody, 4930405E17Rik antibody, AI255929 antibody, CPR antibody, Cpu antibody, pCPB antibody, zgc:112493 antibody, carboxypeptidase B2 antibody, carboxypeptidase B2 (plasma) antibody, CPB2 antibody, Cpb2 antibody, cpb2 antibody
- 背景
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Synonyms: Carboxypeptidase B like protein, Carboxypeptidase U, CarboxypeptidaseB2, Carboxypeptidase B2, CarboxypeptidaseU, CP B2, CPB 2, CPB2, CPU, PCPB, Plasma carboxypeptidase B, Plasma carboxypeptidase B2, Procarboxypeptidase B, Procarboxypeptidase R, Procarboxypeptidase U, TAFI, Thrombin activable fibrinolysis inhibitor, Thrombin activatable fibrinolysis inhibitor.
Background: This protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues. It circulates in plasma as a zymogen with molecular weight of 55 kDa (401 amino acid residues, pI 5.0). Being activated by thrombin-thrombomodulin complex during blood coagulation, it exerts carboxypeptidase activity. Activated carboxypeptidase B2 removes C-terminal lysine residues from fibrin, which is necessary for plasminogen binding to fibrin. This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot. The concentration in plasma of healthy people is 5-10 μg/mL. High plasma levels were found in patients with stable angina pectoris and angiographically verified coronary artery disease. Elevated concentration in blood is considered as a risk factor for venous thrombosis. A deficiency might contribute to the severity of bleeding disorders in hemophilias A and B, and decreased levels are found in chronic liver disease.
- 基因ID
- 1361
- 途径
- Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
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