CDC14B 抗体 (AA 65-160) (AbBy Fluor® 488)
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- 抗原 See all CDC14B 抗体
- CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))
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抗原表位
- AA 65-160
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC14B antibody is conjugated to AbBy Fluor® 488
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CDC14B
- 亚型
- IgG
- Top Product
- Discover our top product CDC14B Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))
- 别名
- CDC14B (CDC14B 产品)
- 别名
- CDC14B antibody, 2810432N10Rik antibody, A530086E13Rik antibody, AA472821 antibody, CDC14B3 antibody, Cdc14B1 antibody, Cdc14B2 antibody, hCDC14B antibody, Dual specificity protein phosphatase CDC14B antibody, dual specificity protein phosphatase CDC14B antibody, cell division cycle 14B antibody, CDC14 cell division cycle 14B antibody, Bm1_19115 antibody, LOAG_10083 antibody, CDC14B antibody, cdc14b antibody, Cdc14b antibody
- 背景
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Synonyms: CDC14B3, Cdc14B1, Cdc14B2, hCDC14B, Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, CDC14B
Background: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.
- 基因ID
- 8555
- UniProt
- O60729
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