CCDC40 抗体 (AA 851-950) (Cy5)
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- 抗原 See all CCDC40 抗体
- CCDC40 (Coiled-Coil Domain Containing 40 (CCDC40))
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抗原表位
- AA 851-950
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CCDC40 antibody is conjugated to Cy5
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CCDC4
- 亚型
- IgG
- Top Product
- Discover our top product CCDC40 Primary Antibody
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anti-Coiled-Coil Domain Containing 40 (CCDC40) (AA 1-478) antibody
CCDC40 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CCDC40 (Coiled-Coil Domain Containing 40 (CCDC40))
- 别名
- CCDC40 (CCDC40 产品)
- 别名
- CILD15 antibody, B930008I02Rik antibody, im:7149866 antibody, lok antibody, si:dkey-237i9.5 antibody, wu:fb11d02 antibody, coiled-coil domain containing 40 antibody, CCDC40 antibody, Ccdc40 antibody, ccdc40 antibody
- 背景
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Synonyms: CCD40_HUMAN, ccdc 40, CCDC40, Coiled coil domain containing 40, coiled-coil domain containing 40, Coiled-coil domain-containing protein 40.
Background: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39.Involvement in disease:Defects in CCDC40 are the cause of primary ciliary dyskinesia type 15 (CILD15) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
- 基因ID
- 55036
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