CCDC39 抗体 (AbBy Fluor® 488)
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- 抗原 See all CCDC39 抗体
- CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CCDC39 antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Cow,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CCDC39
- 亚型
- IgG
- Top Product
- Discover our top product CCDC39 Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))
- 别名
- Ccdc39 (CCDC39 产品)
- 别名
- 4921507O14Rik antibody, AI447426 antibody, AI844750 antibody, D3Ertd789e antibody, b2b1304Clo antibody, b2b1735Clo antibody, RGD1306277 antibody, CILD14 antibody, FAP59 antibody, coiled-coil domain containing 39 antibody, flagellar associated protein antibody, Ccdc39 antibody, CCDC39 antibody, ccdc39 antibody, FAP59 antibody
- 背景
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Synonyms: CCD39_HUMAN, Ccdc39, Coiled-coil domain-containing protein 39.
Background: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly.Tissue specificity:Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis.Involvement in disease:Defects in CCDC39 are the cause of primary ciliary dyskinesia type 14 (CILD14) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
- 基因ID
- 339829
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