ASB3 抗体 (AA 21-120) (Cy5)
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- 抗原 See all ASB3 抗体
- ASB3 (Ankyrin Repeat and SOCS Box-Containing 3 (ASB3))
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抗原表位
- AA 21-120
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASB3 antibody is conjugated to Cy5
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Dog,Cow,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ASB3
- 亚型
- IgG
- Top Product
- Discover our top product ASB3 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ASB3 (Ankyrin Repeat and SOCS Box-Containing 3 (ASB3))
- 别名
- ASB3 (ASB3 产品)
- 别名
- ASB-3 antibody, 2400011J03Rik antibody, Asb-3 antibody, fi36b12 antibody, zgc:56163 antibody, wu:fi36b12 antibody, ASB3 antibody, DKFZp459D0910 antibody, asb-3 antibody, asb3 antibody, ankyrin repeat and SOCS box containing 3 antibody, ankyrin repeat and SOCS box-containing 3 antibody, ankyrin repeat and SOCS box containing 3 S homeolog antibody, ASB3 antibody, Asb3 antibody, asb3 antibody, asb3.S antibody
- 背景
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Synonyms: Ankyrin repeat and SOCS box containing 3, Ankyrin repeat and SOCS box containing protein 3, Ankyrin repeat and SOCS box protein 3, ASB-3, ASB3, ASB3_HUMAN, Weakly similar to ankyrin brain variant 2.
Background: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
- 基因ID
- 51130
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