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APIP 抗体 (AA 151-242) (AbBy Fluor® 350)

APIP 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN883026
发货至: 中国
  • 抗原 See all APIP 抗体
    APIP (APAF1 Interacting Protein (APIP))
    抗原表位
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 151-242
    适用
    • 34
    • 14
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 32
    • 2
    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APIP antibody is conjugated to AbBy Fluor® 350
    应用范围
    • 13
    • 12
    • 12
    • 7
    • 5
    • 4
    • 3
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human APIP
    亚型
    IgG
    Top Product
    Discover our top product APIP Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    APIP (APAF1 Interacting Protein (APIP))
    别名
    Apaf1 Interacting Protein (APIP 产品)
    别名
    APIP2 antibody, CGI29 antibody, MMRP19 antibody, dJ179L10.2 antibody, hAPIP antibody, CGI-29 antibody, Mmrp19 antibody, RGD1564562 antibody, zgc:103619 antibody, APAF1 interacting protein antibody, APAF1 interacting protein S homeolog antibody, APIP antibody, Apip antibody, apip antibody, apip.S antibody
    背景

    Synonyms: MTNB_HUMAN, Apaf1 Interacting Protein, APIP2, CG129, CGI 29, MMRP19, MTRu 1 P dehydratase, Probable methylthioribulose 1 phosphate dehydratase.

    Background: The mammalian homologues of the key cell death gene CED 4 in C. elegans has been identified recently from human and mouse and designated Apaf1 (for apoptosis protease activating factor 1). Apaf1 binds to cytochrome c (Apaf2) and caspase 9 (Apaf3), which leads to caspase 9 activation. Activated caspase 9 in turn cleaves and activates caspase 3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. A new Apaf1 Interacting Protein (APIP) also known as CG129 and MMRP19, has been identified as a negative regulator of ischemic injury. APIP competes with Caspase 9 binding site of Apaf1. APIP is predicted to code for a 204 amino acid. An isoform of APIP, APIP2 encodes a 242 amino acid protein, which is an alternative splicing variant differing in its N terminus from APIP. APIP transcript is ubiquitously expressed in most adult tissue with high expression in skeletal muscle, heart, and kidney.

    基因ID
    51074
    途径
    Methionine Biosynthetic Process
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