ADAM11 抗体 (AA 351-450) (AbBy Fluor® 555)
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- 抗原 See all ADAM11 抗体
- ADAM11 (ADAM Metallopeptidase Domain 11 (ADAM11))
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抗原表位
- AA 351-450
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADAM11 antibody is conjugated to AbBy Fluor® 555
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Cow,Sheep
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ADAM11
- 亚型
- IgG
- Top Product
- Discover our top product ADAM11 Primary Antibody
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anti-ADAM Metallopeptidase Domain 11 (ADAM11) (AA 230-333) antibody
ADAM11 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D4 unconjugated
anti-ADAM Metallopeptidase Domain 11 (ADAM11) (AA 290-430) antibodyADAM11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 11 (ADAM11) antibodyADAM11 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 11 (ADAM11) (AA 230-333) antibodyADAM11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ADAM11 (ADAM Metallopeptidase Domain 11 (ADAM11))
- 别名
- ADAM11 (ADAM11 产品)
- 别名
- DKFZp459F101 antibody, AW060611 antibody, Mdc antibody, MDC antibody, mdc antibody, mdc11a antibody, xMDC11 antibody, ADAM metallopeptidase domain 11 antibody, a disintegrin and metallopeptidase domain 11 antibody, ADAM metallopeptidase domain 11 L homeolog antibody, ADAM11 antibody, adam11 antibody, Adam11 antibody, adam11.L antibody
- 背景
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Synonyms: A disintegrin and metalloproteinase domain 11, ADA11_HUMAN, MDC, Metalloproteinase like, disintegrin like, and cysteine rich protein.
Background: ADAM11 was first described as MDC (Metalloproteinase-like disintergin-like cysteine-rich protein) from analysis of human brain libraries, in search of brain-specific proteins. Two splice variants with different carboxyterminal ends were described. The message was found only in the brain in this publication. Another group identified ADAM11 in the human brain, where ADAM11 was thought to be involved in cell migration and spatial patterning. ADAM11 was mapped to 17q21.3, a region of interest for breast cancer, and mutations in ADAM11 are associated with some breast cancers. Retinoic acid caused a doubling in ADAM11 message levels over 24 hours in NT2/D1 cells, a human embryonic carcinoma cell line. ADAM11 null mutant mice have deficits in spatial learning and motor coordination, although they did have normal cell migration and differentiation during development. ADAM11 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the full-length ADAM11 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a spacer region, then the transmembrane domain and a short cytoplasmic domain.
- 基因ID
- 4185
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