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C-JUN 抗体 (pTyr170) (AbBy Fluor® 488)

JUN 适用: 人 WB, FACS, IF (cc) 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN879107
发货至: 中国
  • 抗原 See all C-JUN (JUN) 抗体
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    抗原表位
    • 46
    • 41
    • 38
    • 27
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    • 16
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    • 16
    • 9
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    • 1
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    • 1
    pTyr170
    适用
    • 388
    • 203
    • 186
    • 33
    • 27
    • 22
    • 17
    • 16
    • 16
    • 12
    • 11
    • 7
    • 5
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    • 1
    • 1
    宿主
    • 382
    • 14
    • 1
    克隆类型
    • 360
    • 37
    多克隆
    标记
    • 189
    • 22
    • 14
    • 13
    • 13
    • 12
    • 12
    • 12
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    • 12
    • 7
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    This C-JUN antibody is conjugated to AbBy Fluor® 488
    应用范围
    • 262
    • 131
    • 126
    • 98
    • 63
    • 50
    • 46
    • 43
    • 42
    • 23
    • 11
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    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of Tyr170
    亚型
    IgG
    Top Product
    Discover our top product JUN Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    别名
    c-Jun (JUN 产品)
    别名
    AP-1 antibody, AP1 antibody, c-Jun antibody, fj36h07 antibody, wu:fj36h07 antibody, zgc:65863 antibody, Junc antibody, c-jun antibody, CG2275 antibody, D-Jun antibody, D-jun antibody, D-jun/Jra antibody, DJUN antibody, DJun antibody, Djun antibody, Dmel\\CG2275 antibody, JRA antibody, JUN antibody, Jun antibody, V antibody, cJun antibody, d-JRA antibody, d-Jun antibody, d-jun antibody, dAP-1 antibody, dJRA antibody, dJUN antibody, dJra antibody, dJun antibody, djun antibody, dm-Jun antibody, jra antibody, jun antibody, l(2)46Ef antibody, l(2)IA109 antibody, l(2R)IA109 antibody, Jun proto-oncogene, AP-1 transcription factor subunit antibody, jun proto-oncogene S homeolog antibody, jun proto-oncogene antibody, Jun-related antigen antibody, jun proto-oncogene L homeolog antibody, JUN antibody, Jun antibody, jun.S antibody, jun antibody, Jra antibody, jun.L antibody
    背景

    Synonyms: c-Jun phospho Y170, p-c-Jun phospho Y170, c-Jun Tyr170, Jun oncogene, JUN, Activator Protein 1, AP 1, AP1, AP-1, Enhancer Binding Protein AP1, Jun Activation Domain Binding Protein, JUN protein, JUNC, p39, Proto oncogene cJun, Transcription Factor AP1, V jun avian sarcoma virus 17 oncogene homolog, vJun Avian Sarcoma Virus 17 Oncogene Homolog, JUN_HUMAN, Transcription factor AP-1, Activator 1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog.

    Background: The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.

    基因ID
    3725
    途径
    MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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