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LLGL1 + LLGL2 (pSer650), (pSer654) 抗体 (AbBy Fluor® 647)

适用: 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 647
产品编号 ABIN876759
发货至: 中国
  • 抗原
    LLGL1 + LLGL2
    抗原表位
    pSer650, pSer654
    适用
    大鼠
    宿主
    • 14
    克隆类型
    • 14
    多克隆
    标记
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AbBy Fluor® 647
    应用范围
    • 14
    • 12
    • 12
    • 3
    • 3
    • 3
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Guinea Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from mouse LLGL1 around the phosphorylation site of Ser650+Ser654
    亚型
    IgG
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    LLGL1 + LLGL2
    别名
    LLGL1 + LLGL2+
    背景

    Synonyms: LLGL1 + LLGL2 phospho S650 + S654, LLGL1 + LLGL2 phospho Ser650 + Ser654, p-LLGL1 + p-LLGL2 S650 + S654, p-LLGL1/LLGL2 Ser650 + Ser654, p-LLGL1/LLGL2 S650 + S654, p-LLGL1/LLGL2 Ser650/654, DLG4, HGL, HUGL, HUGL1, lethal giant larvae homolog 1, lethal giant larvae homolog 2, Lethal2 giant larvae protein homolog 1, Lethal2 giant larvae protein homolog 2, LGL2, LLGL, L2GL1_HUMAN, L2GL2_HUMAN.

    Background: LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

    基因ID
    3996
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