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ERAP1 抗体 (AA 651-730)

ERAP1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN873313
发货至: 中国
  • 抗原 See all ERAP1 抗体
    ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
    抗原表位
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 651-730
    适用
    • 32
    • 17
    • 15
    • 1
    • 1
    宿主
    • 30
    • 2
    克隆类型
    • 28
    • 4
    多克隆
    标记
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERAP1 antibody is un-conjugated
    应用范围
    • 19
    • 14
    • 10
    • 10
    • 7
    • 4
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ARTS1
    亚型
    IgG
    Top Product
    Discover our top product ERAP1 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
    别名
    ARTS1 (ERAP1 产品)
    别名
    MGC166160 antibody, DKFZp469C044 antibody, ARTS-1 antibody, A-LAP antibody, ALAP antibody, APPILS antibody, ARTS1 antibody, ERAAP antibody, ERAAP1 antibody, PILS-AP antibody, PILSAP antibody, Arts1 antibody, PILSA antibody, Appils antibody, endoplasmic reticulum aminopeptidase 1 antibody, endoplasmic reticulum aminopeptidase 1b antibody, ERAP1 antibody, erap1 antibody, erap1b antibody, Erap1 antibody
    背景

    Synonyms: Endoplasmic reticulum aminopeptidase 1, A LAP, A-LAP, Adipocyte derived leucine aminopeptidase, Adipocyte-derived leucine aminopeptidase, ALAP, Aminopeptidase PILS, APPILS, ARTS 1, ARTS-1, Arts1, Endoplasmic reticulum aminopeptidase 1, ERAAP, ERAP 1, Erap1, ERAP1_HUMAN, PILS AP, PILS-AP, PILSA, PILSAP, Puromycin insensitive leucyl specic aminopeptidase, Puromycin-insensitive leucyl-specic aminopeptidase, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator, VEGF-induced aminopeptidase.

    Background: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.

    基因ID
    51752
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