ERAP1 抗体 (AA 651-730)
-
- 抗原 See all ERAP1 抗体
- ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
-
抗原表位
- AA 651-730
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ERAP1 antibody is un-conjugated
-
应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ARTS1
- 亚型
- IgG
- Top Product
- Discover our top product ERAP1 Primary Antibody
-
-
- 应用备注
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
- 别名
- ARTS1 (ERAP1 产品)
- 别名
- MGC166160 antibody, DKFZp469C044 antibody, ARTS-1 antibody, A-LAP antibody, ALAP antibody, APPILS antibody, ARTS1 antibody, ERAAP antibody, ERAAP1 antibody, PILS-AP antibody, PILSAP antibody, Arts1 antibody, PILSA antibody, Appils antibody, endoplasmic reticulum aminopeptidase 1 antibody, endoplasmic reticulum aminopeptidase 1b antibody, ERAP1 antibody, erap1 antibody, erap1b antibody, Erap1 antibody
- 背景
-
Synonyms: Endoplasmic reticulum aminopeptidase 1, A LAP, A-LAP, Adipocyte derived leucine aminopeptidase, Adipocyte-derived leucine aminopeptidase, ALAP, Aminopeptidase PILS, APPILS, ARTS 1, ARTS-1, Arts1, Endoplasmic reticulum aminopeptidase 1, ERAAP, ERAP 1, Erap1, ERAP1_HUMAN, PILS AP, PILS-AP, PILSA, PILSAP, Puromycin insensitive leucyl specic aminopeptidase, Puromycin-insensitive leucyl-specic aminopeptidase, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator, VEGF-induced aminopeptidase.
Background: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.
- 基因ID
- 51752
-