KLHL13 抗体 (AA 351-450)
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- 抗原 See all KLHL13 抗体
- KLHL13 (Kelch-Like 13 (KLHL13))
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抗原表位
- AA 351-450
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适用
- 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KLHL13 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 斑马鱼
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human KLHL13
- 亚型
- IgG
- Top Product
- Discover our top product KLHL13 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- KLHL13 (Kelch-Like 13 (KLHL13))
- 别名
- KLHL13 (KLHL13 产品)
- 别名
- 1200009K10Rik antibody, AI451128 antibody, Bklhd2 antibody, D130072F20Rik antibody, mKIAA1309 antibody, BKLHD2 antibody, Kelch-like protein 13 antibody, kelch-like 13 antibody, kelch like family member 13 antibody, kelch like family member 9 antibody, kelch-like family member 13 antibody, klh13 antibody, Klhl13 antibody, KLHL13 antibody, KLHL9 antibody
- 背景
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Synonyms: Kelch-like protein 13, BTB and kelch domain-containing protein 2, KLH13_HUMAN.
Background: KLHL13 (kelch like 13), also known as BKLHD2 (BTB and kelch domain containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate specific adapter of an E3 ubiquitin protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin mediated proteolysis. Via its BTB and C terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL3 ligase.
- 基因ID
- 90293
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