Crossover junction endonuclease EME1 (EME1) (AA 412-500) 抗体
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- 抗原 See all Crossover junction endonuclease EME1 (EME1) 抗体
- Crossover junction endonuclease EME1 (EME1)
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抗原表位
- AA 412-500
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Sheep,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human EME1
- 亚型
- IgG
- Top Product
- Discover our top product EME1 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- Crossover junction endonuclease EME1 (EME1)
- 别名
- EME1 (EME1 产品)
- 别名
- 6820428D13 antibody, essential meiotic structure-specific endonuclease 1 antibody, Eme1 antibody
- 背景
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Synonyms: Crossover junction endonuclease EME1, Eme1 essential meiotic endonuclease 1 homolog 1 S. pombe, EME1, S. pombe, homolog of, 1, essential meiotic endonuclease 1 homolog 1 S pombe, Essential Meiotic Endonuclease 1 Homolog 1, essential meiotic endonuclease 1 homolog 2, Essential meiotic endonuclease 1, S. pombe, homolog of, 1, hMMS4, homolog of yeast EME1 endonuclease, MMS4, MMS4 homolog, MMS4L, EME1_HUMAN.
Background: EME1 complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein (MUS81) to form an endonuclease complex which cleaves branched DNA structures, especially those arising during stalled DNA replication. The protein may be involved in repairing DNA damage and in maintaining genomic stability. It interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. Alternative splicing results in multiple transcript variants.
- 基因ID
- 146956
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