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S1PR1 抗体 (AA 51-150)

Name: S1PR1 抗体 (AA 51-150)
SKU: ABIN872844
Availability: OutOfStock

S1PR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Rat heart lysates probed with S1P1 Polyclonal Antibody, unconjugated at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 90 minutes at 37°C. (S1PR1 抗体 (AA 51-150))

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-EDG1/CD363/S1P1 Polyclonal Antibody, Unconjugated (ABIN872844) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (S1PR1 抗体 (AA 51-150))

ELISA

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-EDG1/CD363/S1P1 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (S1PR1 抗体 (AA 51-150))

IHC (p)

ELISA

4 images

(1 reference)

产品编号 ABIN872844

发货至: 中国

Datasheet as PDF

抗原 See all S1PR1 抗体

S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
抗原表位
14

8

7

6

5

5

5

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 51-150
适用
92

62

43

7

4

3

3

3

2

1

1

1
人, 小鼠, 大鼠
宿主
90

8
兔
Compatible Secondaries
克隆类型
81

17
多克隆
标记
51

5

5

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This S1PR1 antibody is un-conjugated
应用范围
69

37

16

13

13

12

11

8

3

3

3

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human S1P1

亚型

IgG

Top Product

Discover our top product S1PR1 Primary Antibody
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (C-Term) antibody
S1PR1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 311-382) antibody
S1PR1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-47) antibody
S1PR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E12 unconjugated

anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) antibody
S1PR1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1E3H5 unconjugated

anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-47) antibody
S1PR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F11 unconjugated

anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (Internal Region) antibody
S1PR1 适用: 人, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (Ser311) antibody
S1PR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-382) antibody
S1PR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 17-30), (Extracellular), (N-Term) antibody
S1PR1 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ICC, LCI 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (pThr236) antibody
S1PR1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Xiao, Fu, Xu, Feng, Sun, Ye: "Fingolimod Suppresses a Cascade of Core Vicious Cycle in Dry Eye NOD Mouse Model: Involvement of Sphingosine-1-Phosphate Receptors in Infiltrating Leukocytes." in: Investigative ophthalmology & visual science, Vol. 58, Issue 14, pp. 6123-6132, (2017) (PubMed).
抗原

S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

别名

S1P1 (S1PR1 产品)

别名

CD363 antibody, CHEDG1 antibody, D1S3362 antibody, ECGF1 antibody, EDG-1 antibody, EDG1 antibody, S1P1 antibody, AI849002 antibody, Edg1 antibody, Lpb1 antibody, S1p antibody, S1p1 antibody, S1P receptor 1 antibody, S1P receptor Edg-1 antibody, edg1 antibody, etID43307.22 antibody, s1p1 antibody, wu:fb98f05 antibody, s1pr1 antibody, xts1p1 antibody, sphingosine-1-phosphate receptor 1 antibody, sphingosine-1-phosphate receptor 1 L homeolog antibody, S1PR1 antibody, S1pr1 antibody, s1pr1 antibody, s1pr1.L antibody

背景

Synonyms: EDG1, S1P1, CD363, ECGF1, EDG-1, CHEDG1, D1S3362, Sphingosine 1-phosphate receptor 1, S1P receptor 1, Endothelial differentiation G-protein coupled receptor 1, Sphingosine 1-phosphate receptor Edg-1, S1P receptor Edg-1, S1PR1
Background: G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralization and bone homeostasis (By similarity). Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.

基因ID

1901

UniProt

P21453

途径

Signaling Events mediated by VEGFR1 and VEGFR2