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FAM21C 抗体 (AA 1201-1318)

FAM21C 适用: 大鼠 IF (cc), IF (p), IHC (fro), IHC (p), ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN872706
发货至: 中国
  • 抗原 See all FAM21C 抗体
    FAM21C (Family with Sequence Similarity 21, Member C (FAM21C))
    抗原表位
    • 14
    • 2
    AA 1201-1318
    适用
    • 14
    • 2
    大鼠
    宿主
    • 14
    • 2
    克隆类型
    • 16
    多克隆
    标记
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAM21C antibody is un-conjugated
    应用范围
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Cow,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human FAM21C
    亚型
    IgG
    Top Product
    Discover our top product FAM21C Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    FAM21C (Family with Sequence Similarity 21, Member C (FAM21C))
    别名
    Fam21c (FAM21C 产品)
    别名
    Fam21 antibody, NP61201 antibody, FAM21A antibody, VPEF antibody, A130095H06 antibody, C530005J20Rik antibody, D6Wsu116e antibody, fam21c antibody, wu:fb78c06 antibody, zgc:153646 antibody, WASH complex subunit 2C antibody, WASH complex subunit 2 antibody, family with sequence similarity 21, member C antibody, Washc2c antibody, WASHC2C antibody, Washc2 antibody, washc2c antibody
    背景

    Synonyms: FAM21A, Family with sequence similarity 21 member C, Hypothetical protein LOC253725, KIAA0592, Protein FAM21C, FA21C_HUMAN.

    Background: Playing a essential role in the fission of tubules that serve as transport intermediates during endosome sorting, the WASH complex is present at the surface of endosomes and functions to recruit and activate the Arp2/3 complex for induction of actin polymerization. FAM21, Putative WASH complex subunit FAM21, is a component of the WASH complex. Having undergone evolutionary duplication, four highly homologous family members exist including FAM21A, FAM21B, FAM21C and FAM21D. FAM21 links the WASH complex to endosomes and is required for WASM-dependent retromer-mediated sorting. Also, by directly interacting with CapZ, FAM21 inhibits its anti-capping activity, thereby regulating actin dynamics.

    基因ID
    253725
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