FAM3C 抗体 (AA 151-227)
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- 抗原 See all FAM3C 抗体
- FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))
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抗原表位
- AA 151-227
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FAM3C antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Cow,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FAM3C
- 亚型
- IgG
- Top Product
- Discover our top product FAM3C Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))
- 别名
- FAM3C (FAM3C 产品)
- 别名
- ILEI antibody, D6Wsu176e antibody, Ilei antibody, wu:fb99h11 antibody, wu:fi35h03 antibody, zgc:55444 antibody, zgc:77090 antibody, family with sequence similarity 3 member C antibody, family with sequence similarity 3, member C antibody, family with sequence similarity 3 member C L homeolog antibody, fam3c antibody, FAM3C antibody, Fam3c antibody, fam3c.L antibody
- 背景
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Synonyms: Fam3c, FAM3C_HUMAN, family with sequence similarity 3, member C, GS3786,ILEI, Interleukin-like EMT inducer, Predicted osteoblast protein, Protein FAM3C.
Background: ILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates with oncogenic Ras to cause TGF-independent Emt and its overexpression is correlated with the invasion, metastasis and survival in a variety of cancers.
- 基因ID
- 10447
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