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AICDA 抗体 (AA 101-198)

AICDA 适用: 人 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN872554
发货至: 中国
  • 抗原 See all AICDA 抗体
    AICDA (Activation-Induced Cytidine Deaminase (AICDA))
    抗原表位
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 101-198
    适用
    • 33
    • 16
    • 7
    • 2
    • 1
    宿主
    • 28
    • 2
    • 1
    • 1
    • 1
    克隆类型
    • 29
    • 4
    多克隆
    标记
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AICDA antibody is un-conjugated
    应用范围
    • 23
    • 16
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human AICDA
    亚型
    IgG
    Top Product
    Discover our top product AICDA Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Demberg, Mohanram, Musich, Brocca-Cofano, McKinnon, Venzon, Robert-Guroff: "Loss of marginal zone B-cells in SHIVSF162P4 challenged rhesus macaques despite control of viremia to low or undetectable levels in chronic infection." in: Virology, Vol. 484, pp. 323-333, (2015) (PubMed).

  • 抗原
    AICDA (Activation-Induced Cytidine Deaminase (AICDA))
    别名
    AICDA (AICDA 产品)
    别名
    AID antibody, ARP2 antibody, CDA2 antibody, HIGM2 antibody, Aid antibody, Arp2 antibody, aid antibody, AICDA antibody, arp2 antibody, cda2 antibody, higm2 antibody, xlaid antibody, activation induced cytidine deaminase antibody, activation-induced cytidine deaminase antibody, activation-induced cytidine deaminase L homeolog antibody, AICDA antibody, Aicda antibody, aicda antibody, aicda.L antibody
    背景

    Synonyms: AID, ARP2, CDA2, HIGM2, HEL-S-284, Single-stranded DNA cytosine deaminase, Activation-induced cytidine deaminase, Cytidine aminohydrolase, AICDA

    Background: Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.

    基因ID
    57379
    UniProt
    Q9GZX7
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Production of Molecular Mediator of Immune Response
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