PGLYRP1 抗体 (AA 65-150)
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- 抗原 See all PGLYRP1 抗体
- PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
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抗原表位
- AA 65-150
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PGLYRP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PGRPS
- 亚型
- IgG
- Top Product
- Discover our top product PGLYRP1 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
- 别名
- PGRPS (PGLYRP1 产品)
- 别名
- PGLYRP1 antibody, PGLYRP antibody, pgrp antibody, tag7 antibody, pgrps antibody, pglyrp antibody, pgrp-s antibody, tnfsf3l antibody, MGC108330 antibody, MGC108469 antibody, PGRP-SC1a antibody, si:dkey-113g17.4 antibody, si:ch211-202c21.3 antibody, PGRP antibody, PGRP-S antibody, PGRPS antibody, TAG7 antibody, TNFSF3L antibody, Pglyrp antibody, Tag7 antibody, Tasg7 antibody, Tnfsf3l antibody, Pgrp antibody, peptidoglycan recognition protein 1 antibody, peptidoglycan recognition protein 1 L homeolog antibody, peptidoglycan recognition protein 5 antibody, PGLYRP1 antibody, pglyrp1.L antibody, pglyrp1 antibody, pglyrp5 antibody, Pglyrp1 antibody
- 背景
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Synonyms: Peptidoglycan recognition protein 1, Peptidoglycan recognition protein, PGLYRP, PGLYRP1, PGRP, PGRP S, PGRP-PEN, PGRP-S, TAG7, TNFSF 3L, TNFSF3L, PGRP1_HUMAN.
Background: The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRPS, PGRPIA, and PGRP-I-beta) define a new family of human pattern recognition molecules. PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood. PGRPS is present in neutrophils and inhibits growth of Gram-positive bacteria and, therefore, may function as a neutrophil antibacterial protein. However, PGRPS may have another, as yet unidentified function because in humans it is expressed in the bone marrow 50100 times higher than in neutrophils.
- 基因ID
- 8993
- 途径
- Activation of Innate immune Response
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