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Myosin VIIA 抗体 (AA 851-950)

MYO7A 适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN872519
发货至: 中国
  • 抗原 See all Myosin VIIA (MYO7A) 抗体
    Myosin VIIA (MYO7A)
    抗原表位
    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 851-950
    适用
    • 35
    • 25
    • 2
    • 1
    人, 小鼠
    宿主
    • 33
    • 2
    克隆类型
    • 33
    • 2
    多克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Myosin VIIA antibody is un-conjugated
    应用范围
    • 14
    • 12
    • 12
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Pig,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Myosin VIIa
    亚型
    IgG
    Top Product
    Discover our top product MYO7A Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    Myosin VIIA (MYO7A)
    别名
    Myosin 7a (MYO7A 产品)
    背景

    Synonyms: DFNB2, MYU7A, NSRD2, USH1B, DFNA11, MYOVIIA, Unconventional myosin-VIIa, MYO7A

    Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

    基因ID
    4647
    UniProt
    Q13402
    途径
    Sensory Perception of Sound
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