FAM33A 抗体 (AA 2-88)
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- 抗原 See all FAM33A 抗体
- FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))
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抗原表位
- AA 2-88
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FAM33A antibody is un-conjugated
- 应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SKA2
- 亚型
- IgG
- Top Product
- Discover our top product FAM33A Primary Antibody
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anti-Spindle and Kinetochore-Associated Protein 2 (FAM33A) (AA 1-121) antibody
FAM33A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spindle and Kinetochore-Associated Protein 2 (FAM33A) (N-Term) antibodyFAM33A 适用: 人, 小鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindle and Kinetochore-Associated Protein 2 (FAM33A) (AA 9-37), (N-Term) antibodyFAM33A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31468 unconjugated
anti-Spindle and Kinetochore-Associated Protein 2 (FAM33A) (AA 16-45), (N-Term) antibodyFAM33A 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))
- 别名
- SKA2 (FAM33A 产品)
- 别名
- FAM33A antibody, 1110001A07Rik antibody, C78640 antibody, Fam33a antibody, RGD1307084 antibody, fam33a antibody, spindle and kinetochore associated complex subunit 2 antibody, Spindle and kinetochore-associated protein 2 antibody, SKA2 antibody, Ska2 antibody, ska2 antibody
- 背景
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Synonyms: FAM33A, Family with sequence similarity 33, member A, FLJ12758, MGC110975, Protein FAM33A, SKA 2, SKA2, SKA2_HUMAN, Spindle and kinetochore associated complex subunit 2, Spindle and kinetochore associated protein 2, Spindle and kinetochore-associated protein 2, Spindle and KT kinetochore associated 2, Spindle and KT associated 2.
Background: Ska2 (spindle and kinetochore associated complex subunit 2), also known as FAM33A, is a 121 amino acid component of the Ska1 complex, a microtubule-binding subcomplex of the outer kinetochore that is critical for proper chromosome segregation. The Ska1 complex is a component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. Localized to the outer kinetochore and spindle microtubules during cell proliferation, Ska2 is essential for spindle checkpoint silencing and exit from mitosis. Downregulation of Ska2 leads to delayed recruitment of MAD2, a component of the mitotic spindle checkpoint, to several kinetochores resulting in occasional loss of individual chromosomes from the metaphase plate. Ska2 is encoded by a gene located on human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.
- 途径
- M Phase
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