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CEMIP 抗体 (AA 101-200)

CEMIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN872432
发货至: 中国
  • 抗原 See all CEMIP 抗体
    CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))
    抗原表位
    • 14
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    适用
    • 39
    • 31
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 35
    • 4
    克隆类型
    • 37
    • 2
    多克隆
    标记
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CEMIP antibody is un-conjugated
    应用范围
    • 32
    • 12
    • 12
    • 10
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human TMEM2L
    亚型
    IgG
    Top Product
    Discover our top product CEMIP Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Liang, Fang, Yang, Song: "Silencing of CEMIP suppresses Wnt/β-catenin/Snail signaling transduction and inhibits EMT program of colorectal cancer cells." in: Acta histochemica, Vol. 120, Issue 1, pp. 56-63, (2017) (PubMed).

  • 抗原
    CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))
    别名
    CEMIP (CEMIP 产品)
    别名
    CCSP1 antibody, TMEM2L antibody, 3110012M15Rik antibody, mKIAA1412 antibody, 12H19.01.T7 antibody, 6330404C01Rik antibody, AY007814 antibody, Kiaa1199 antibody, KIAA1199 antibody, cell migration inducing hyaluronan binding protein antibody, transmembrane protein 2 antibody, cell migration inducing protein, hyaluronan binding antibody, CEMIP antibody, Tmem2 antibody, TMEM2 antibody, Cemip antibody
    背景

    Synonyms: CCSP1, TMEM2L, KIAA1199, Cell migration-inducing and hyaluronan-binding protein, CEMIP, HYBID

    Background: Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.

    基因ID
    57214
    UniProt
    Q8WUJ3
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