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INSRR 抗体 (AA 801-900)

INSRR 适用: 人 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN872418
发货至: 中国
  • 抗原 See all INSRR 抗体
    INSRR (Insulin Receptor-Related Receptor (INSRR))
    抗原表位
    • 14
    • 9
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 801-900
    适用
    • 54
    • 22
    • 7
    • 1
    • 1
    • 1
    宿主
    • 58
    • 1
    克隆类型
    • 57
    • 2
    多克隆
    标记
    • 21
    • 6
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INSRR antibody is un-conjugated
    应用范围
    • 41
    • 37
    • 18
    • 13
    • 12
    • 6
    • 3
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Insulin receptor-related protein beta chain
    亚型
    IgG
    Top Product
    Discover our top product INSRR Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    INSRR (Insulin Receptor-Related Receptor (INSRR))
    别名
    INSRR (INSRR 产品)
    别名
    IRR antibody, Irr antibody, Sirr antibody, MGC68585 antibody, INSRR antibody, insulin receptor related receptor antibody, insulin receptor-related receptor antibody, insulin receptor related receptor L homeolog antibody, INSRR antibody, Insrr antibody, insrr.L antibody, insrr antibody
    背景

    Synonyms: INSRR, Insulin receptor related receptor precursor, IR related receptor, IRR, Sirr, Insulin receptor-related protein, IR-related receptor, Insulin receptor-related protein beta chain, INSRR_HUMAN.

    Background: The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesn?t bind any of IR and IGF-1R known ligands. In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown.

    基因ID
    3645
    途径
    RTK signaling
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