KDM4A 抗体 (AA 75-155)
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- 抗原 See all KDM4A 抗体
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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抗原表位
- AA 75-155
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KDM4A antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human JMJD2A/KDM4A
- 亚型
- IgG
- Top Product
- Discover our top product KDM4A Primary Antibody
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
- 别名
- JMJD2A (KDM4A 产品)
- 别名
- JMJD2A antibody, JHDM3A antibody, JMJD2 antibody, TDRD14A antibody, D4Ertd222e antibody, Jmjd2 antibody, Jmjd2a antibody, mKIAA0677 antibody, lysine demethylase 4A antibody, lysine-specific demethylase 4A antibody, lysine (K)-specific demethylase 4A antibody, KDM4A antibody, LOC100228023 antibody, Kdm4a antibody
- 背景
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Synonyms: JMJ2A, JmjC domain containing histone demethylation protein 3A, JmjC domain-containing histone demethylation protein 3A, JMJD2, jumonji C domain containing histone demethylase 3A, Jumonji domain containing 2, Jumonji domain containing 2A, Jumonji domain containing protein 2A, Jumonji domain-containing protein 2A, KDM4A, KDM2A_HUMAN, KIAA0677, Lysine-specic demethylase 4A.
Background: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
- 途径
- Warburg Effect
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