BAT3 抗体 (AA 1042-1132)
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- 抗原 See all BAT3 抗体
- BAT3 (Large Proline-Rich Protein BAT3 (BAT3))
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抗原表位
- AA 1042-1132
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BAT3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human BAT3/BAG6
- 亚型
- IgG
- Top Product
- Discover our top product BAT3 Primary Antibody
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anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-1126) antibody
BAT3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-1126) antibodyBAT3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibodyBAT3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 943-992) antibodyBAT3 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-200) antibodyBAT3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (Internal Region) antibodyVerified BAT3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-200) antibodyBAT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibodyBAT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibodyBAT3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- BAT3 (Large Proline-Rich Protein BAT3 (BAT3))
- 别名
- BAG6 (BAT3 产品)
- 背景
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Synonyms: family molecular chaperone regulator 6, BAG-6, BAG6, Bag6, BAG6_HUMAN, BCL2-associated athanogene 6, D6S52E, G3, HLA B associated transcript 3, HLA-B-associated transcript 3, Large proline-rich protein BAG6, Protein G3, Protein Scythe.
Background: Chaperone that plays a key role in various processes such as apoptosis, insertion of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane and regulation of chromatin. Acts in part by regulating stability of proteins and their degradation by the proteasome. Participates in endoplasmic reticulum stress-induced apoptosis via its interaction with AIFM1/AIF by regulating AIFM1/AIF stability and preventing its degradation. Also required during spermatogenesis for synaptonemal complex assembly via its interaction with HSPA2, by inhibiting polyubiquitination and subsequent proteasomal degradation of HSPA2. Required for selective ubiquitin-mediated degradation of defective nascent chain polypeptides by the proteasome. In this context, may play a role in immuno-proteasomes to generate antigenic peptides via targeted degradation, thereby playing a role in antigen presentation in immune response. Key component of the BAG6/BAT3 complex, a cytosolic multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. BAG6/BAT3 acts by facilitating TA membrane proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins and transfers them to ASNA1/TRC40 for targeting to the endoplasmic reticulum membrane.
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