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Importin 4 抗体 (AA 231-330)

IPO4 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN872364
发货至: 中国
  • 抗原 See all Importin 4 (IPO4) 抗体
    Importin 4 (IPO4)
    抗原表位
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 231-330
    适用
    • 19
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 19
    克隆类型
    • 19
    多克隆
    标记
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Importin 4 antibody is un-conjugated
    应用范围
    • 9
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Importin4
    亚型
    IgG
    Top Product
    Discover our top product IPO4 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    Importin 4 (IPO4)
    别名
    Importin4 (IPO4 产品)
    别名
    Imp4 antibody, 8430408O15Rik antibody, AA409693 antibody, Imp4a antibody, RanBP4 antibody, importin 4 antibody, IPO4 antibody, Ipo4 antibody
    背景

    Synonyms: Imp4, Imp4b, Importin 4b, Importin-4, Importin-4b, Ipo4, IPO4_HUMAN, Ran binding protein 4, Ran-binding protein 4, RanBP4, IPO4_HUMAN.

    Background: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

    基因ID
    79711
    途径
    Protein targeting to Nucleus
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