NOD1 抗体 (AA 51-150)
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- 抗原 See all NOD1 抗体
- NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
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抗原表位
- AA 51-150
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NOD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CARD4
- 亚型
- IgG
- Top Product
- Discover our top product NOD1 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior." in: Molecular psychiatry, Vol. 22, Issue 2, pp. 257-266, (2016) (PubMed).
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The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior." in: Molecular psychiatry, Vol. 22, Issue 2, pp. 257-266, (2016) (PubMed).
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- 抗原
- NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
- 别名
- CARD4 (NOD1 产品)
- 别名
- CARD4 antibody, CLR7.1 antibody, NLRC1 antibody, C230079P11 antibody, Card4 antibody, F830007N14Rik antibody, Nlrc1 antibody, RGD1562269 antibody, nucleotide binding oligomerization domain containing 1 antibody, nucleotide-binding oligomerization domain containing 1 antibody, NOD1 antibody, Nod1 antibody
- 背景
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Synonyms: CARD4, NLRC1, CLR7.1, Nucleotide-binding oligomerization domain-containing protein 1, Caspase recruitment domain-containing protein 4, NOD1
Background: Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathway activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB. Recruits NLRP10 to the cell membrane following bacterial infection.
- 基因ID
- 10392
- UniProt
- Q9Y239
- 途径
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Inflammasome
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