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SRRT 抗体 (AA 721-800)

SRRT 适用: 大鼠 WB, ELISA, IF (p), IHC (fro), IHC (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN872317
发货至: 中国
  • 抗原 See all SRRT 抗体
    SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
    抗原表位
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 721-800
    适用
    • 26
    • 7
    • 4
    • 1
    大鼠
    宿主
    • 23
    • 2
    • 1
    克隆类型
    • 26
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This SRRT antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ARS2
    亚型
    IgG
    Top Product
    Discover our top product SRRT Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
    别名
    ARS2 (SRRT 产品)
    别名
    CG7843 antibody, Dmel\\CG7843 antibody, anon-WO0118547.166 antibody, ars2 antibody, ars2-A antibody, serrate antibody, ARS2 antibody, ASR2 antibody, 2810019G02Rik antibody, ASR2A antibody, ASR2B antibody, ASR2C antibody, ASR2D antibody, Ars2 antibody, Asr2 antibody, MGC92060 antibody, CHUNP6881 antibody, zgc:92060 antibody, Arsenic resistance protein 2 antibody, serrate, RNA effector molecule S homeolog antibody, serrate, RNA effector molecule antibody, serrate RNA effector molecule homolog (Arabidopsis) antibody, Ars2 antibody, srrt.S antibody, SRRT antibody, Srrt antibody, srrt antibody
    背景

    Synonyms: ARS2 protein, Arsenate resistance protein ARS2, Arsenite resistance protein 2, Arsenite resistance protein, ASR2, MGC126427, Serrate, Serrate RNA effector molecule homolog Arabidopsis, Serrate RNA effector molecule homolog, SRRT, SRRT_HUMAN.

    Background: ARS2(Arsenite resistance protein 2) confers arsenite resistance. The protein belongs to the ARS2 family. Arsenic is a human carcinogen whose mechanism of action is unknown. The arsenite acts as a comutagen by interfering with DNA repair. Two genes, ASR1(Arsenite resistance protein 1) and ASR2 (Arsenite resistance protein 2), confer arsenite resistance to arsenite-sensitive cells. ASR1 shows almost complete homology with the rat fau gene, a tumor suppressor gene which contains a ubiquitin like region fused to S30 ribosomal protein. Arsenite inhibits ubiquitin dependent proteolysis. The tumor suppressor fau gene product or some other aspect of the ubiquitin system may be a target for arsenic toxicity and that disruption of the ubiquitin system may contribute to the genotoxicity and carcinogenicity of arsenite.

    基因ID
    51593
    途径
    Notch Signaling, Stem Cell Maintenance
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