SRRT 抗体 (AA 721-800)
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- 抗原 See all SRRT 抗体
- SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
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抗原表位
- AA 721-800
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SRRT antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ARS2
- 亚型
- IgG
- Top Product
- Discover our top product SRRT Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
- 别名
- ARS2 (SRRT 产品)
- 别名
- CG7843 antibody, Dmel\\CG7843 antibody, anon-WO0118547.166 antibody, ars2 antibody, ars2-A antibody, serrate antibody, ARS2 antibody, ASR2 antibody, 2810019G02Rik antibody, ASR2A antibody, ASR2B antibody, ASR2C antibody, ASR2D antibody, Ars2 antibody, Asr2 antibody, MGC92060 antibody, CHUNP6881 antibody, zgc:92060 antibody, Arsenic resistance protein 2 antibody, serrate, RNA effector molecule S homeolog antibody, serrate, RNA effector molecule antibody, serrate RNA effector molecule homolog (Arabidopsis) antibody, Ars2 antibody, srrt.S antibody, SRRT antibody, Srrt antibody, srrt antibody
- 背景
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Synonyms: ARS2 protein, Arsenate resistance protein ARS2, Arsenite resistance protein 2, Arsenite resistance protein, ASR2, MGC126427, Serrate, Serrate RNA effector molecule homolog Arabidopsis, Serrate RNA effector molecule homolog, SRRT, SRRT_HUMAN.
Background: ARS2(Arsenite resistance protein 2) confers arsenite resistance. The protein belongs to the ARS2 family. Arsenic is a human carcinogen whose mechanism of action is unknown. The arsenite acts as a comutagen by interfering with DNA repair. Two genes, ASR1(Arsenite resistance protein 1) and ASR2 (Arsenite resistance protein 2), confer arsenite resistance to arsenite-sensitive cells. ASR1 shows almost complete homology with the rat fau gene, a tumor suppressor gene which contains a ubiquitin like region fused to S30 ribosomal protein. Arsenite inhibits ubiquitin dependent proteolysis. The tumor suppressor fau gene product or some other aspect of the ubiquitin system may be a target for arsenic toxicity and that disruption of the ubiquitin system may contribute to the genotoxicity and carcinogenicity of arsenite.
- 基因ID
- 51593
- 途径
- Notch Signaling, Stem Cell Maintenance
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