Sortilin 1 抗体 (AA 731-831)
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- 抗原 See all Sortilin 1 (SORT1) 抗体
- Sortilin 1 (SORT1)
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抗原表位
- AA 731-831
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Sortilin 1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Pig,Horse,Guinea Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Sortilin
- 亚型
- IgG
- Top Product
- Discover our top product SORT1 Primary Antibody
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anti-Sortilin 1 (SORT1) (AA 203-299) antibody
SORT1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Sortilin 1 (SORT1) (AA 520-760) antibodySORT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 328-457) antibodySORT1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 320-335), (Extracellular Domain) antibodySORT1 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 50-320) antibodySORT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 203-299) antibodySORT1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 320-335), (Extracellular Domain) antibody (FITC)SORT1 适用: 人, 大鼠, 小鼠 FACS 宿主: 兔 Polyclonal FITC
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- Sortilin 1 (SORT1)
- 别名
- Ntr3 (SORT1 产品)
- 背景
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Synonyms: SORT1,100 kDa NT receptor, Glycoprotein 95 Short name: Gp95, Neurotensin receptor 3 Short name: NT3 Short name: NTR3, SORT_HUMAN
Background: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.
- 基因ID
- 6272
- UniProt
- Q99523
- 途径
- Neurotrophin Signaling Pathway
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