NOD2 抗体 (AA 251-350)
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- 抗原 See all NOD2 抗体
- NOD2 (Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
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抗原表位
- AA 251-350
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NOD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CARD15
- 亚型
- IgG
- Top Product
- Discover our top product NOD2 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- NOD2 (Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
- 别名
- NOD2 (NOD2 产品)
- 别名
- ACUG antibody, BLAU antibody, CARD15 antibody, CD antibody, CLR16.3 antibody, IBD1 antibody, NLRC2 antibody, NOD2B antibody, PSORAS1 antibody, Card15 antibody, F830032C23Rik antibody, Nlrc2 antibody, caspase recruitment domain 15 protein antibody, nucleotide binding oligomerization domain containing 2 antibody, nucleotide-binding oligomerization domain containing 2 antibody, TTHERM_01951320 antibody, NOD2 antibody, Nod2 antibody
- 背景
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Synonyms: ACUG, Arthrocutaneouveal granulomatosis, BLAU, CARD15, Caspase recruitment domain protein 15, Caspase recruitment domain-containing protein 15, IBD1, Inflammatory bowel disease protein 1, LRR containing protein, LRR-containing protein, Nod2, NOD2 protein, NOD2_HUMAN, NOD2B, nucleotide binding oligomerization domain 2, nucleotide-binding oligomerization domain 2, Nucleotide-binding oligomerization domain-containing protein 2, PSORAS1.
Background: Defects in NOD2 are the cause of sarcoidosis early-onset (EOS) . EOS is a form of sarcoidosis manifesting in children younger than 4 years of age. Sarcoidosis is an idiopathic, systemic, inflammatory disease characterized by the formation of immune granulomas in involved organs. Granulomas predominantly invade the lungs and the lymphatic system, but also skin, liver, spleen, eyes and other organs may be involved. Early-onset sarcoidosis is quite rare and has a distinct triad of skin, joint and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, early-onset sarcoidosis is progressive and in many cases causes severe complications, such as blindness, joint destruction and visceral involvement.
- 基因ID
- 64127
- UniProt
- Q9HC29
- 途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome
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