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MAP2K4 抗体 (AA 352-356)
MAP2K4
适用: 人, 小鼠, 大鼠
WB
宿主: 兔
Polyclonal
unconjugated
MAP2K4抗体详情
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抗原
See all MAP2K4 抗体
MAP2K4
(Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
抗原表位
All epitopes for MAP2K4 抗体
AA 352-356
适用
All reactivities for MAP2K4 抗体
人, 小鼠, 大鼠
宿主
All hosts for MAP2K4 抗体
兔
克隆类型
All clonalities for MAP2K4 抗体
多克隆
标记
All conjugates for MAP2K4 抗体
This MAP2K4 antibody is un-conjugated
应用范围
All applications for MAP2K4 抗体
Western Blotting (WB)
特异性
The antibody detects endogenous levels of total MAP2K4 protein.
纯化方法
Affinity purified
免疫原
Peptide sequence around AA 352-356 (E-S-K-R-P) derived from Human MAP2K4. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Discover our top product MAP2K4 Primary Antibody
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使用细节
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应用备注
Western blotting: 1:500-1:1000
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C/-20 °C
储存方法
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
MAP2K4目标详情
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抗原
MAP2K4
(Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
别名
MAP2K4 (MAP2K4 产品 )
别名
JNKK antibody, JNKK1 antibody, MAPKK4 antibody, MEK4 antibody, MKK4 antibody, PRKMK4 antibody, SAPKK-1 antibody, SAPKK1 antibody, SEK1 antibody, SERK1 antibody, SKK1 antibody, Sek1 antibody, Serk1 antibody, MKK4A-l antibody, map2k4 antibody, zgc:136500 antibody, jnkk antibody, mek4 antibody, mkk4 antibody, sek1 antibody, jnkk1 antibody, serk1 antibody, xmek2 antibody, mapkk4 antibody, prkmk4 antibody, 142758_at antibody, CG9738 antibody, CT27508 antibody, D-MKK4 antibody, DMKK4 antibody, Dmel\\CG9738 antibody, JNKK2 antibody, Mpk4 antibody, SEK1/MKK4 antibody, dMKK4 antibody, dMkk4 antibody, hep antibody, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 antibody, ATMEK4 antibody, ATMKK4 antibody, F19C24.26 antibody, F19C24_26 antibody, MAP KINASE KINASE 4 antibody, mitogen-activated protein kinase kinase 4 antibody, MKK4B antibody, zgc:194486 antibody, mitogen-activated protein kinase kinase 4 antibody, mitogen-activated protein kinase kinase 4a antibody, MAP kinase kinase 4 antibody, mitogen activated protein kinase kinase 4 antibody, mitogen-activated protein kinase kinase 4b antibody, MAP2K4 antibody, Map2k4 antibody, map2k4a antibody, map2k4 antibody, Mkk4 antibody, MKK4 antibody, map2k4b antibody
背景
SAPK/Erk kinase (SEK1), also known as MKK4 or Jun kinase kinase (JNKK), activates the MAP kinase homologues SAPK and JNK in response to various cellular stresses and inflamatory cytokines (1-3). Activation of SEK1 occurs through MEKK phosphorylation of serine and threonine residues at positions 257 and 261, respectively. Like MEK, SEK is a dual-specificity protein kinase that phosphorylates SAPK/JNK at a conserved T*PY* site in its activation loop (4). Phosphorylation by Akt at Ser80 inhibits SEK1 and suppresses stress-activated signal transduction
分子量
44 kDa
基因ID
6416
NCBI登录号
NP_003001
UniProt
P45985
途径
MAPK Pathway , TLR signaling , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , Toll-Like Receptors Cascades , BCR Signaling
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