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p53 抗体

TP53 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN866051
发货至: 中国
  • 抗原 See all p53 (TP53) 抗体
    p53 (TP53) (Tumor Protein P53 (TP53))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This p53 antibody is un-conjugated
    应用范围
    • 662
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    Western Blotting (WB)
    特异性
    This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of N-terminal residues of p53.
    交叉反应
    人, 小鼠
    产品特性
    Positive Control: A431. Cellular Localization: Cytoplasm, nucleus
    纯化方法
    Immunogen affinity purified
    亚型
    IgG
    Top Product
    Discover our top product TP53 Primary Antibody
  • 应用备注
    WB: 1:500-1,000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5mg/ml
    缓冲液
    1xTBS (pH7.4), 0.5% BSA, 25% Glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    p53 (TP53) (Tumor Protein P53 (TP53))
    别名
    p53 (TP53 产品)
    背景
    P53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. It acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. P53 is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is frequently mutated or inactivated in about 60% of cancers
    分子量
    ~70kDa
    UniProt
    Q91XH8
    途径
    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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