Solute Carrier Family 14 (Urea Transporter, Kidney) Member 2 (SLC14A2) (AA 911-929) 抗体
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- 抗原 See all Solute Carrier Family 14 (Urea Transporter, Kidney) Member 2 (SLC14A2) 抗体
- Solute Carrier Family 14 (Urea Transporter, Kidney) Member 2 (SLC14A2)
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抗原表位
- AA 911-929
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 特异性
- Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney. Isoform 3 and isoform 4 are expressed in both the inner and outer renal medulla.,Detects ~97 and 127 kDa.
- 交叉反应
- 小鼠, 大鼠
- 纯化方法
- Peptide Affinity Purified
- 免疫原
- Produced against a synthetic peptide mapped to the C-terminal tail (amino acids 911-929) of rat UT-A1 (antibody designation L194)
- Top Product
- Discover our top product SLC14A2 Primary Antibody
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- 应用备注
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- WB (1:1000)
- IHC (1:25)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN863205 was sufficient for detection of UT-A1 in 20 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- Solute Carrier Family 14 (Urea Transporter, Kidney) Member 2 (SLC14A2)
- 别名
- UT-A1 (SLC14A2 产品)
- 别名
- HUT2 antibody, UT-A2 antibody, UT2 antibody, UTA antibody, UTR antibody, hUT-A6 antibody, Slc14a2T antibody, Slc14a2_v4 antibody, UrT1-C antibody, UrT1-D antibody, testSymbol antibody, UT-A1 antibody, UT-A3 antibody, solute carrier family 14 member 2 antibody, solute carrier family 14 (urea transporter), member 2 antibody, SLC14A2 antibody, Slc14a2 antibody
- 背景
- UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates trans-epithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts. (The antibody also recognizes a second protein from the UT-A gene driven by transcription from an alternative promoter and expressed in the thin descending limb of Henle, viz. UT-A2) (1, 2).
- 基因ID
- 54302
- NCBI登录号
- NP_062220
- UniProt
- Q62668
- 途径
- Response to Water Deprivation
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